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Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research

Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research

In analyzing the effects of experimental drugs on the brain, mass spectrometry is the sole technique for identifying the presence and structure of neuropeptides-substances that indicate the effect of the drug. This book specifically explains how to apply the technology to this pr... read full description below.

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ISBN 9780471354932
Published 18 April 2002 by John Wiley & Sons Australia Lt
Format Hardback
Author(s) Edited by Silberring, Jerzy
Edited by Ekman, Rolf
Series Wiley Series on Mass Spectrometry
Availability Title is temporarily out of stock

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Full details for this title

ISBN-13 9780471354932
ISBN-10 0471354937
Stock Available
Status Title is temporarily out of stock
Publisher John Wiley & Sons Australia Lt
Imprint John Wiley & Sons Inc
Publication Date 18 April 2002
International Publication Date 16 May 2002
Publication Country United States United States
Format Hardback
Author(s) Edited by Silberring, Jerzy
Edited by Ekman, Rolf
Series Wiley Series on Mass Spectrometry
Category Non-Fiction (Child / Teen)
Pharmacology
Chemical Spectroscopy, Spectrochemistry
Biochemistry
Biotechnology
Number of Pages 576
Dimensions Width: 161mm
Height: 243mm
Spine: 33mm
Weight 1g
Interest Age 19+ years
Reading Age 19+ years
Library of Congress Mass spectrometry
NBS Text Chemistry
ONIX Text College/higher education;Professional and scholarly
Dewey Code 543.0873
Catalogue Code Not specified

Description of this Book

Mass spectrometry is a powerful analytical technique that is used to identify unknown compounds, to quantify known materials, and to elucidate the structural and chemical properties of molecules. In analyzing the effects of experimental drugs on the brain, it is the sole technique for identifying the presence and structure of neuropeptides--substances that indicate the effect of the drug. Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research specifically explains how to apply the technology to this process. Because the book is written by mass spectrometry users, as opposed to mass spectrometrists, the focus remains on practical applications of the technique. The authors demonstrate how mass spectrometry works, how to apply the technique to research, which types of instrumentation should be used for particular requirements, and how to plan experiments. Readers will learn why mass spectrometry provides more outcome features than other techniques in neuropeptide analysis, including simultaneous detection, identification of substances present in mixtures, and sequence information even when the residues are modified, blocked, or unusual. Among the chapters in this comprehensive text are: -Sequencing of Peptides by Nanospray Mass Spectrometry -Laser-Machined Microdevices for Mass Spectrometry -Electron Capture Dissociation of Peptides -Synthesis of Combinatorial Peptide Libraries -Analysis of Tissues That Reflect Nervous System Disease Doctoral students, researchers, and industry professionals in pharmacology, chemistry, biochemistry/biotechnology, and medicine will find Mass Spectrometry and Hyphenated

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Awards, Reviews & Star Ratings

NZ Review ...a vital addition to a mass spectrometry library...the authors have done an excellent job... (Journal of the American Society for Mass Spectrometry, 2003) ...useful...a particularly timely reference that focuses on recent progress of mass spectrometry in protein research... (Journal of the American Chemical Society, Vol. 125, No. 20, 2003)

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Author's Bio

JERZY SILBERRING, PhD, is Professor of Biochemistry at the Chemistry and Regional Laboratory of the Jagiellonian University in Krakow, Poland. ROLF EKMAN, PhD, is Professor of Neurochemistry at the Institute of Clinical Neuroscience of the Goeteborg University in Sweden.

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