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Quantitative Biological and Clinical Mass Spectrometry: An Introduction

Quantitative Biological and Clinical Mass Spectrometry: An Introduction (Hardback)

By Mallet, Anthony I.

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A basic overview of mass spectrometry relevant to life and health science applications, illustrated throughout with relevant case studies This introductory text provides information and assistance to new users of mass spectrometry (MS) working in clinical or biochemical fields wh...o are faced with implementing and designing quantitative mass spectrometric assays for a variety of classes of molecules of biological interest. It presents a detailed discussion on how to optimize measurement parameters for a candidate reference quantitative analysis, including calibration procedures, sensitivity, reproducibility, speed of assay and compliance with regulatory authorities. Quantitative Biological and Clinical Mass Spectrometry uses examples where development has not been immediately successful but where unforeseen problems have arisen and describes the strategies used to solve these. Advances in addressing the very large numbers of clinical samples that arise on routine screening programs such as those involved in inborn errors of metabolism studies are discussed. Direct mass spectrometric based analyses applicable to point of care testing (POCT) situations are also covered. The book concludes with a short section on possible novel developments, bibliography, references, and a glossary of terms. Shows how the presence of false results can be detected and understoodDescribes the parts of modern instruments from sample introduction through ionization, mass analysis and detection, and the variety of techniques of tandem mass spectrometryDiscusses the requirement for specificity in an assay methodFully illustrated throughoutHighly relevant to all key areas of mass spectrometric analysis Quantitative Biological and Clinical Mass Spectrometry appeals to those newly exposed to the use of combined chromatography and mass spectrometry for analysis of biological material and to scientists experienced in automated clinical analysis using immunoassays or who are new to mass spectrometry.
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ISBN 9781119281207
Released NZ 29 Jun 2018
Publisher John Wiley & Sons Australia Lt
Format Hardback
Availability
Back Order Indent title (sourced internationally), Allow 8-12 weeks due to Covid 19 freight delays

Full details for this title

ISBN-13 9781119281207
Stock Available
Status Back Order Indent title (sourced internationally), Allow 8-12 weeks due to Covid 19 freight delays
Publisher John Wiley & Sons Australia Lt
Imprint Wiley-Blackwell
Released 29 Jun 2018
Publication Country United States United States
Format Hardback
Author(s) By Mallet, Anthony I.
Category Chemistry
Chemical Spectroscopy, Spectrochemistry
Biology & Life Sciences
Number of Pages 224
Dimensions Width: 155mm
Height: 236mm
Spine: 16mm
Dewey Code 570.28
Weight 464g
Interest Age General Audience
Reading Age General Audience
Library of Congress Biochemical engineering, Clinical chemistry, Mass spectrometry
NBS Text Life Sciences: General
ONIX Text Professional and scholarly

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