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              Biomarker Analysis in Clinical Trials with R
               

              Biomarker Analysis in Clinical Trials with R (Hardback)

              By Rabbee, Nusrat

              • RRP: $245.00
              • $245.00
              • Pub Date
                28 Apr 20

              Biomarker Analysis in Clinical Trials with R offers practical guidance to statisticians in the pharmaceutical industry on how to incorporate biomarker data analysis in clinical trial studies. The book discusses the appropriate statistical methods for evaluating pharmacodynamic, p...redictive and surrogate biomarkers for delivering increased value in the drug development process. The topic of combining multiple biomarkers to predict drug response using machine learning is covered. Featuring copious reproducible code and examples in R, the book helps students, researchers and biostatisticians get started in tackling the hard problems of designing and analyzing trials with biomarkers. Features: Analysis of pharmacodynamic biomarkers for lending evidence target modulation. Design and analysis of trials with a predictive biomarker. Framework for analyzing surrogate biomarkers. Methods for combining multiple biomarkers to predict treatment response. Offers a biomarker statistical analysis plan. R code, data and models are given for each part: including regression models for survival and longitudinal data, as well as statistical learning models, such as graphical models and penalized regression models. Nusrat Rabbee is a biostatistician and data scientist at Eisai, Inc., where she leads Statistical Methodology in Neurology. Her research is in the development of statistical methods and computational tools for personalized treatment. She has co-discovered the RLMM algorithm for genotyping Affymetrix SNP chips and co-invented a high-dimensional molecular signature for cancer. She has spent over sixteen years in the pharmaceutical and diagnostics industry. She has taught Statistics at UC Berkeley for four years.
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              ISBN 9781138368835
              Released NZ 28 Apr 2020
              Publisher Taylor & Francis Ltd
              Interest Age 16+ years
              Series Chapman & Hall/CRC Biostatistics Series
              Availability
              Available for pre-order, ships once released
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              Blockchain for Medical Research: Accelerating Trust in Healthcare
               

              Blockchain for Medical Research: Accelerating Trust in Healthcare (Paperback)

              By Manion, Sean T.; Bizouati-Kennedy, Yael

              • RRP: $91.99
              • $91.99
              • Pub Date
                27 Apr 20

              It takes 17 years on average to bring new health ideas into evidence-based clinical practice. The growing replicability crisis in science further delays these new miracles. Blockchain can improve replicability and hasten the knowledge translation process. This book is about scien...ce, its value to our health, and how we can use blockchain to improve its quality and impact. The book will look at science and medicine from an insider's perspective, and describe the processes, successes, shortcomings and opportunities for advancement for the lay audience. It will give the reader a non-technical look at the emerging world of blockchain technology; what it is, where it is useful, and how it can improve science and health. It will lay out a roadmap for this application to transform how we develop knowledge about disease and accelerate cures to improve our lives. In the first part, the authors look at science as a process and how this drives advancement in medicine. They'll then shed a light on some of science's shortcomings, including the reproducibility crisis and problems with misaligned incentives (i.e. publish or perish). The book applies a breakdown of critical components to the functional steps in the scientific process and outlines how the open science movement is looking to improve these. It will also highlight the limit of these fixes with current technology, incentives and structure of science. The second part, looks at the history of distributed ledgers from pre-computer versions to the current applications of blockchain/distributed ledger technology and gives an overview of use cases for the technology across industries, including finance, manufacturing and healthcare. Additional focus will be provided to the application challenges with more complex data systems and the need for a contributing network of users. The third and last part, looks at the principle of a distributed autonomous organization (DAO) applied to the health sciences. The authors examine how thi
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              ISBN 9780367347468
              Released NZ 27 Apr 2020
              Publisher Taylor & Francis Ltd
              Interest Age 16+ years
              Availability
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              Biotechnology Fundamentals Third Edition
               

              Biotechnology Fundamentals Third Edition (Hardback)

              By Khan, Firdos Alam

              • RRP: $217.00
              • $217.00
              • Pub Date
                21 Apr 20

              After successful launching of first and second editions of Biotechnology Fundamentals, we thought let us find out the feedbacks from our esteemed readers, faculty members, and students about their experiences and after receiving their suggestions and recommendation we thought it ...would be great idea to write 3rd edition of the book. Being a teacher of biotechnology, I always wanted a book which covers all aspects of biotechnology, right from basics to applied and industrial levels. In our previous editions, we have included all topics of biotechnology which are important and fundamentals for students learning. One of the important highlights of the book that it has dedicated chapter for the career aspects of biotechnology and you may agree that many students eager to know what are career prospects they have in biotechnology. There are a great number of textbooks available that deal with molecular biotechnology, microbial biotechnology, industrial biotechnology, agricultural biotechnology, medical biotechnology, or animal biotechnology independently; however, there is not a single book available that deals with all aspects of biotechnology in one book. Today the field of biotechnology is moving with lightening speed. It becomes very important to keep track of all those new information which affect the biotechnology field directly or indirectly. In this book, I have tried to include all the topics which are directly or indirectly related to fields of biotechnology. The book discusses both conventional and modern aspects of biotechnology with suitable examples and gives the impression that the field of biotechnology is there for ages with different names; you may call them plant breeding, cheese making, in vitro fertilization, alcohol fermentation is all the fruits of biotechnology. The primary aim of this book is to help the students to learn biotechnology with classical and modern approaches and take them from basic information to complex topics. There is a total of 2
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              ISBN 9781138612082
              Released NZ 21 Apr 2020
              Publisher Taylor & Francis Ltd
              Interest Age 16+ years
              Availability
              Available for pre-order, ships once released
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              The Inflammation Spectrum: Find Your Food Triggers and Reset Your System
               

              The Inflammation Spectrum: Find Your Food Triggers and Reset Your System (Trade Paperback / Paperback)

              By Cole, Dr Will

              • RRP: $37.99
              • $29.63
              • Save $8.36
              • Pub Date
                31 Dec 19

              The Inflammation Spectrum is a game-changing guide which aids readers to overcome their health woes through doing nutrition the right way.

              ISBN 9781529379129
              Released NZ 31 Dec 2019
              Publisher Hodder & Stoughton
              Interest Age 16+ years
              Availability
              Available for pre-order, ships once released
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              Cardio-Obstetrics: A Practical Guide to Care for Pregnant Cardiac Patients
               

              Cardio-Obstetrics: A Practical Guide to Care for Pregnant Cardiac Patients (Paperback)

              Edited by Hameed, Afshan B.; Wolfe, Diana

              • RRP: $181.00
              • $181.00
              • Pub Date
                4 May 20

              Cardiac disease is one of the leading causes of maternal morbidity and mortality. Catastrophic outcomes typically encountered are due to gaps in knowledge and communication between health care providers. There is a great need for a standardized approach for care of this very high...-risk group of pregnant women. The book encompasses detailed obstetrics and cardiology perspectives that are crucial in the management of the commonly encountered cardiac conditions in pregnancy. This text aims to provide guidance to the whole team caring for a pregnant cardiac patient consisting of obstetricians, maternal-fetal medicine, hospitalists, cardiologists, obstetric anaesthesiologists, emergency physicians, primary care providers and nurses. Features: Cardio Obstetric team organization Preconception counselling and family planning considerations Cardiovascular disease screening and risk stratification of a pregnant cardiac patient Management of a wide spectrum of cardiovascular diagnoses through use of checklists and algorithms in a simple format Essential key points for each cardiac diagnosis
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              ISBN 9781138317918
              Released NZ 4 May 2020
              Publisher Taylor & Francis Ltd
              Interest Age 16+ years
              Availability
              Available for pre-order, ships once released
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              Voice and Communication Therapy with Trans and Non-Binary People: Sharing the Clinical Space
                

              Voice and Communication Therapy with Trans and Non-Binary People: Sharing the Clinical Space (Trade Paperback / Paperback)

              By Mills, Matthew; Stoneham, Gillie; Foreword by Greener, Helen; Barker, Meg-John; Illustrated by Retieff, Charlotte

              • RRP: $59.50
              • $56.52
              • Save $2.98
              • Pub Date
                21 Jul 20

              This book is specifically aimed at Speech and Language Therapists and sets out a range of games, activities, frameworks and exercises to help them develop their skills for working with trans clients. It also focuses on the innovative approach of individual therapy and group thera...py settings, which is important for optimising speech adaptation.
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              ISBN 9781787751040
              Released NZ 21 Jul 2020
              Publisher Jessica Kingsley Publishers
              Interest Age 16+ years
              Availability
              Available for pre-order, ships once internationally released 21 Jul 2020
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              Work Matters: Consulting to leaders and organizations in the Tavistock tradition
               

              Work Matters: Consulting to leaders and organizations in the Tavistock tradition (Hardback)

              By Cardona, Francesca

              • RRP: $247.00
              • $247.00
              • Pub Date
                29 Apr 20

              Work is complicated: It can be fulfilling and exciting, or disappointing and disruptive. We spend most of our adult lives at work; it shapes our identities and provides a context for our creativity and talents. It can be the source of great pleasure - and of profound distress. In... Work Matters, organizational consultant and Tavistock lecturer Francesca Cardona examines our changing relationship with work today. Drawing on case studies from a wide range of individuals and organizations, she considers the dynamics at play in our working lives. Cardona examines how to navigate times of transition, and the balance of power in the work place, while also addressing latent issues such as the effects of shame, the cost of ill-conceived organizational structures and tasks, the interface between the personal and the professional, and the manager's most precious skill: the ability to be psychologically present. Finally, Cardona casts an eye on the consultant's role in helping organizations move forwards in ways that are professionally and personally rewarding. Whether you are a business leader, manager, consultant or student, or simply interested in how your work affects you, Work Matters offers essential insights into an area that occupies so much of our lives.
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              ISBN 9780367313173
              Released NZ 29 Apr 2020
              Publisher Taylor & Francis Ltd
              Interest Age 16+ years
              Availability
              Available for pre-order, ships once released
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              Empathy and the Historical Understanding of the Human Past
               

              Empathy and the Historical Understanding of the Human Past (Hardback)

              By Kohut, Thomas A.

              • RRP: $247.00
              • $247.00
              • Pub Date
                27 Apr 20

              Empathy and the Historical Understanding of the Human Past is a comprehensive consideration of the role of empathy in historical knowledge, informed by the literature on empathy in fields including history, psychoanalysis, psychology, philosophy, and sociology. The book seeks to ...raise the consciousness of historians about empathy, by introducing them to the history of the concept and to its status in fields outside of history. It also seeks to raise the self-consciousness of historians about their use of empathy to know and understand past people. Defining empathy as thinking and feeling, as imagining, one's way inside the experience of others in order to know and understand them, Thomas A. Kohut distinguishes between the external and the empathic observational position, the position of the historical subject. He argues that historians need to be aware of their observational position, of when they are empathizing and when they are not. Indeed, Kohut advocates for the deliberate, self-reflective use of empathy as a legitimate and important mode of historical inquiry. Insightful, cogent, and interdisciplinary, the book will be essential for historians, students of history, and psychoanalysts, as well as those in other fields who seek to seek to know and understand human beings.
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              ISBN 9780367425777
              Released NZ 27 Apr 2020
              Publisher Taylor & Francis Ltd
              Interest Age 16+ years
              Availability
              Available for pre-order, ships once released
              View details for this title
              Empathy and the Historical Understanding of the Human Past
               

              Empathy and the Historical Understanding of the Human Past (Paperback)

              By Kohut, Thomas A.

              • RRP: $70.99
              • $70.99
              • Pub Date
                27 Apr 20

              Empathy and the Historical Understanding of the Human Past is a comprehensive consideration of the role of empathy in historical knowledge, informed by the literature on empathy in fields including history, psychoanalysis, psychology, philosophy, and sociology. The book seeks to ...raise the consciousness of historians about empathy, by introducing them to the history of the concept and to its status in fields outside of history. It also seeks to raise the self-consciousness of historians about their use of empathy to know and understand past people. Defining empathy as thinking and feeling, as imagining, one's way inside the experience of others in order to know and understand them, Thomas A. Kohut distinguishes between the external and the empathic observational position, the position of the historical subject. He argues that historians need to be aware of their observational position, of when they are empathizing and when they are not. Indeed, Kohut advocates for the deliberate, self-reflective use of empathy as a legitimate and important mode of historical inquiry. Insightful, cogent, and interdisciplinary, the book will be essential for historians, students of history, and psychoanalysts, as well as those in other fields who seek to seek to know and understand human beings.
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              ISBN 9780367425784
              Released NZ 27 Apr 2020
              Publisher Taylor & Francis Ltd
              Interest Age 16+ years
              Availability
              Available for pre-order, ships once released
              View details for this title
              Essentials of Delirium: Everything You Really Need to Know for Working in Delirium Care
                

              Essentials of Delirium: Everything You Really Need to Know for Working in Delirium Care (Trade Paperback / Paperback)

              By Rahman, Dr Shibley

              • RRP: $63.50
              • $60.32
              • Save $3.18
              • Pub Date
                18 Jun 20

              This introductory reference guide provides in-depth knowledge and information for students and practitioners to help better their response to patients with delirium. Detailing all aspects of delirium care, including ethical considerations, it is an essential resource in widening ...professional understanding and care improvement.
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              ISBN 9781785926730
              Released NZ 18 Jun 2020
              Publisher Jessica Kingsley Publishers
              Interest Age 16+ years
              Availability
              Available for pre-order, ships once internationally released 18 Jun 2020
              View details for this title
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